CHAPTER 1:Risk Factors and Diseases Causing Chronic Kidney Disease
Topic 2Clinical Practice Guidelines

The National Kidney Foundation, Inc. Kidney Disease Outcomes Quality Initiative (K/DOQI) Work Group for Chronic Kidney Disease (CKD) developed clinical practice guidelines in the year 2000 with an educational grant from Amgen, Inc.

Stages & Classifications

The K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification is a manual developed for healthcare professionals. It provides direction for early identification and appropriate treatment that can result in improved patient outcomes.

 

Chronic kidney disease is defined as either kidney damage or GFR <60 mL/min/1.73 m2 for >=3 months.

Kidney damage is defined as pathologic abnormalities or markers of damage, including abnormalities in blood or urine tests or imaging studies.

GFR (Glomerular Filtration Rate) is a formula used to assess kidney function.

CKD Guidelines

Includes 15 recommendations related to the assessment and classification of chronic kidney disease, association of level of kidney function with complications and a stratification of risk for progression and development of cardiovascular disease in CKD.

StageDescriptionGFR CalculationAction
1Kidney damage with normal or high GFR (Glomerular filtration rate)>=90Diagnosis and treatment, treatment of comorbid conditions, slowing progression and cardiovascular disease risk reduction
2Kidney damage with mild low GFR60-89Estimating progression
3Moderate low GFR30-59Evaluating and treating complications
4Severe low GFR15-29Preparation for renal replacement therapy (RRT)
5Kidney failure<15 (or dialysis)Replacement (if uremia present)

CONTACT INFORMATION

National Kidney Foundation | 30 East 33rd Street New York, NY 10016 | 1-800-622-9010 | www.kidney.org

215 West Illinois, Suite 1C Chicago, IL 60610. P: (312) 321-1500. email: kidney@nkfi.org